Automation Engineer II

Location: San Mateo, CA
Type: onsite
Posted: Sep 1, 2026
Views: 0

✨ AI Summary

BigHat Biosciences, an antibody engineering platform company, is hiring an Automation Engineer II in San Mateo, CA. The role focuses on developing high-throughput automated assay processes and programming robotic systems using Hamilton or OpenTrons platforms. Candidates need a BS or MS in engineering or science with 2+ years of industry experience in laboratory automation. The salary range is $150,000 - $168,000 plus bonus, options, and benefits.

The role: BigHat Biosciences is seeking a highly motivated Automation Engineer II to join our growing team. This position will support the development and scaling of automated workflows within BigHat’s state-of-the-art antibody engineering platform.
  • Lead and contribute to the end-to-end development of high-throughput automated assay processes, spanning a variety of technologies within drug and antibody discovery.
  • Program a variety of laboratory automation instruments and robotic systems.
  • Contribute to the design and development of BigHat’s integrated workcells, with an eye for orders-of-magnitude capacity increase, cost reduction, and increased reliability.
  • Lead troubleshooting efforts, analyze existing workflows, identify bottlenecks, and develop innovative solutions geared for robustness and capacity.
  • Collaborate with software engineering and LIMS teams on building and implementing end-to-end integrated workflows leveraging BigHat’s cutting-edge software stack.
  • Support equipment validation and qualification efforts, including design, execution, and documentation.
  • Contribute to the growth of the automation team, know-how, and expertise at BigHat.
  • BS or MS degree in engineering or science in engineering, biochemistry, or related scientific field, with 2+ years of relevant industry experience.
  • Experience programming or operating automated liquid handling systems, from conception through all phases of development and implementation. Experience with Hamilton and/or OpenTrons platforms preferred but not required.
  • Experience with standard molecular biology and cell biology techniques and/or experience automating drug discovery processes preferred.
  • Functional knowledge in experimental design, bench execution, process documentation, and data analysis.
  • Strong communication skills, and ability to work with people of diverse backgrounds (protein scientists, research associates, data scientists, software engineers, etc.) to scope, develop, and implement solutions.
  • Thrives in a fluid, dynamic start-up environment and enjoys building capabilities from the ground up.
The salary estimated for this position is $150,000 - $168,000 + bonus + options + benefits. Compensation will vary depending on job-related knowledge, skills, and experience. Actual compensation will be confirmed in writing at the time of the offer.

About the Company

Name: bighatbiosciences
Location: San Carlos, California

BigHat Biosciences is a biotechnology company focused on developing advanced antibody therapies using machine learning and synthetic biology. The company's careers page indicates that they are currently hiring and encourages interested candidates to register their interest for future opportunities.

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